Strength but not power training increases soluble alpha klotho levels in pre-frail older adults
Twelve weeks of ST, but not PT, significantly increased circulating sαKL levels in pre-frail older adults. Given the beneficial health effects of increased sαKL, these findings suggest that ST may offer additional biological advantages relevant to healthy aging. sαKL may serve as a promising biomarker for training-induced adaptions, but prospective trials are needed to confirm long-term effects and further clarify underlying mechanisms.
Authors
- Olivia Tausendfreund
- Ralf Schmidmaier (ORCID: https://orcid.org/0000-0003-3541-3588)
- Sabine Schluessel (ORCID: https://orcid.org/0000-0002-2485-8859)
- Júnia Ribeiro de Oliveira Longo Schweizer (ORCID: https://orcid.org/0000-0002-8050-9127)
- Michael Drey (ORCID: https://orcid.org/0000-0001-6709-9672)
- Martin Bidlingmaier (ORCID: https://orcid.org/0000-0002-4681-6668)
- Michaela Rippl (ORCID: https://orcid.org/0009-0000-1583-1577)
- Linda Deißler
- Sebastian Martini (ORCID: https://orcid.org/0000-0003-3663-9239)
- Katharina Mueller
- Laura Welscher
Institutions
- LMU Klinikum (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1016/j.exger.2025.113002
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00