Increasing the quantity of electrical stimulation pulses reduces cortical response inhibition
Decreasing post-stimulation inhibition with increasing pulse quantity may explain why pulse trains more reliably generate perceptual responses. Considering current amplitude and pulse quantity influence different components of the post-stimulation response, developing customized stimulation paradigms may be crucial for optimization of neural prostheses.
Authors
- Maureen A. Hagan (ORCID: https://orcid.org/0000-0003-4965-2731)
- Nicholas S. C. Price (ORCID: https://orcid.org/0000-0001-9404-7704)
- Sabrina J Meikle (ORCID: https://orcid.org/0000-0003-1745-8328)
- Yan T. Wong (ORCID: https://orcid.org/0000-0002-5281-8221)
Institutions
- Discovery Institute (US)
- Australian Regenerative Medicine Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1016/j.brs.2025.103003
- Primary Topic
- Neuroscience and Neural Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council
- National Health and Medical Research Council