LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study
This study demonstrates that LBX2-AS1 promotes CRC angiogenesis and activates the glycolysis <i>via</i> the miR-491-5p/MDK axis. LBX2-AS may serve as a novel diagnostic biomarker and potential therapeutic target for CRC.
Authors
- Chao Li (ORCID: https://orcid.org/0000-0002-4086-575X)
- Guanghai Wu
- Juan Wang (ORCID: https://orcid.org/0000-0002-8476-407X)
- Jing Xu (ORCID: https://orcid.org/0000-0003-0847-4510)
Institutions
- Tianjin First Center Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1080/07853890.2025.2564284
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00