Pre‐operative anaemia, red blood cell transfusion and mortality after cardiac surgery: a Netherlands Heart Registration mediation analysis
A substantial part of the association between pre-operative anaemia and mortality after cardiac surgery is mediated by red blood cell transfusion during hospital stay. The mediating role of red blood cell transfusion was more pronounced in older patients.
Authors
- Maarten ter Horst (ORCID: https://orcid.org/0000-0002-4990-4620)
- Toni Klok
- Jan van Klarenbosch (ORCID: https://orcid.org/0000-0002-5338-1500)
- Thijs C.D. Rettig (ORCID: https://orcid.org/0000-0001-5634-9672)
- Eline A. Vlot (ORCID: https://orcid.org/0000-0002-3538-8880)
- R. Arthur Bouwman (ORCID: https://orcid.org/0000-0002-2051-5947)
- Marcel P. J. De Korte
- Thierry V. Scohy (ORCID: https://orcid.org/0000-0001-7107-1031)
- Alexander J. Spanjersberg (ORCID: https://orcid.org/0000-0002-4731-052X)
- Remco R. Berendsen (ORCID: https://orcid.org/0000-0002-2848-8699)
- Jan Hofland (ORCID: https://orcid.org/0000-0001-8241-7069)
- Lizbeth Burgos Ochoa (ORCID: https://orcid.org/0000-0002-8379-2749)
- Peter G. Noordzij (ORCID: https://orcid.org/0000-0002-7115-8249)
- Susanne Eberl
- Nicobert E. Wietsma
- Sander Bramer
- Bastiaan M. Gerritse (ORCID: https://orcid.org/0000-0002-7520-5372)
- Saskia Houterman (ORCID: https://orcid.org/0000-0002-8680-1380)
- Marieke F. Kingma
- Olaf L. Cremer (ORCID: https://orcid.org/0000-0003-4264-1108)
- Elisabeth M. Groenewegen
- Joost M. van der Maaten (ORCID: https://orcid.org/0000-0001-8796-4977)
- Johannes Haenen
Institutions
- Leiden University (NL)
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Tilburg University (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Medisch Spectrum Twente (NL)
- Erasmus MC (NL)
- Medisch Centrum Leeuwarden (NL)
- Amsterdam UMC Location University of Amsterdam (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- St. Antonius Ziekenhuis (NL)
- Netherlands Heart Registration (NL)
- OLVG (NL)
- Amphia Ziekenhuis (NL)
- Haga Hospital (NL)
- Isala (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Anaesthesia
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1111/anae.70100
- Citations
- 2
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 1.55