Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies
Our cohort studies suggest that elevated salivary theobromine levels are associated with improved periodontal parameters over 7 and 10 years. These results indicate the potential for theobromine-containing products to support periodontal health, warranting further investigation through randomised controlled trials.
Authors
- Birte Holtfreter (ORCID: https://orcid.org/0000-0002-6541-3127)
- Henry Völzke (ORCID: https://orcid.org/0000-0001-7003-399X)
- Karsten Suhre (ORCID: https://orcid.org/0000-0001-9638-3912)
- Peter Meisel (ORCID: https://orcid.org/0000-0002-0243-2435)
- Nele Friedrich (ORCID: https://orcid.org/0000-0002-1017-7622)
- Matthias Nauck (ORCID: https://orcid.org/0000-0002-6678-7964)
- Thomas Kocher (ORCID: https://orcid.org/0000-0001-9605-2822)
- Sebastian‐Edgar Baumeister (ORCID: https://orcid.org/0000-0002-9391-6602)
- Uwe Völker (ORCID: https://orcid.org/0000-0002-5689-3448)
Institutions
- Cornell University (US)
- University of Münster (DE)
- Universitätsmedizin Greifswald (DE)
- Lander Institute (IL)
- Universität Greifswald (DE)
- Weill Cornell Medical College in Qatar (QA)
Publication Details
- Journal
- Journal Of Clinical Periodontology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1111/jcpe.70072
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Qatar Foundation
- Fonds National de la Recherche Luxembourg
- Weill Cornell Medical College
- Qatar National Research Fund
- Weill Cornell Medicine - Qatar