Disentangling the relationship between glucose, insulin and brain health: A <scp>UK</scp> Biobank study
Genetically proxied postprandial hyperglycaemia contributes to increased Alzheimer's risk in mid-life, warranting replication in other populations and ancestries to confirm and clarify underlying mechanisms.
Authors
- Liam Smeeth (ORCID: https://orcid.org/0000-0002-9168-6022)
- Christopher T. Rentsch (ORCID: https://orcid.org/0000-0002-1408-7907)
- Victoria Garfield (ORCID: https://orcid.org/0000-0002-5127-0890)
- Krishnan Bhaskaran (ORCID: https://orcid.org/0000-0001-5364-8757)
- Andrew C. Mason (ORCID: https://orcid.org/0000-0001-7719-8500)
- Reecha Sofat (ORCID: https://orcid.org/0000-0002-0242-6115)
- Nasri Fatih
- Nish Chaturvedi (ORCID: https://orcid.org/0000-0002-6211-2775)
Institutions
- University of Liverpool (GB)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- MRC Unit for Lifelong Health and Ageing (GB)
- University College London (GB)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1111/dom.70353
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- Diabetes Research and Wellness Foundation