Association between serum sodium and the risk of sepsis-related liver injury: a cross-sectional study based on the MIMIC-IV database

In critically ill adults with sepsis, SNa showed a nonlinear inverse association with SRLI, with a threshold around 135 mmol/L. Incorporating sodium into clinical assessment and stratification may be informative; multicenter prospective cohorts are warranted to confirm clinical utility.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-12-13
DOI
https://doi.org/10.1186/s12879-025-12330-2
Primary Topic
Electrolyte and hormonal disorders
Type
article
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article

Association between serum sodium and the risk of sepsis-related liver injury: a cross-sectional study based on the MIMIC-IV database

Guiyun Li, Yulia Lin, Xiaomin Liang, Shuiqing Gui et al.
BMC Infectious Diseases
Electrolyte and hormonal disorders
article

Association between serum sodium and the risk of sepsis-related liver injury: a cross-sectional study based on the MIMIC-IV database

Guiyun Li, Yulia Lin, Xiaomin Liang, Shuiqing Gui, Lin Zhang, Ying Li, Yongwen Feng, Yanhong Chen, Di Ren, Sha Wen, Jiang Mei
article en

Abstract

In critically ill adults with sepsis, SNa showed a nonlinear inverse association with SRLI, with a threshold around 135 mmol/L. Incorporating sodium into clinical assessment and stratification may be informative; multicenter prospective cohorts are warranted to confirm clinical utility.

BMC Infectious DiseasesVol. 26(1)
ShenZhen People’s Hospital (CN), Shenzhen Bao'an District People's Hospital (CN), Shenzhen Second People's Hospital (CN)
Openalex Percentile: Top 41%
Electrolyte and hormonal disorders
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Association between serum sodium and the risk of sepsis-related liver injury: a cross-sectional study based on the MIMIC-IV database — Guiyun Li, Yulia Lin, et al. · BMC Infectious Diseases (2025) | TGRS Research Map | TGRS