Cost‐effectiveness of fenfluramine as add‐on treatment in the management of Dravet Syndrome: A real‐world multicenter study
Dravet syndrome is a severe and rare type of epilepsy that can be very hard on patients and their families. It also puts a great burden on healthcare systems. A new treatment, fenfluramine (FFA), helps better control seizures. Although FFA increases drug treatment costs, this cost is actually balanced out by reduced emergency visits and hospital stays for severe seizures, leading to overall lower healthcare expenses.
Authors
- Nicola Pietrafusa (ORCID: https://orcid.org/0000-0003-2446-796X)
- Michela Quintiliani (ORCID: https://orcid.org/0000-0002-8278-6953)
- Renzo Guerrini (ORCID: https://orcid.org/0000-0002-7272-7079)
- Alessandra Boncristiano (ORCID: https://orcid.org/0000-0003-4270-5781)
- Francesca Darra (ORCID: https://orcid.org/0000-0002-1062-8438)
- Rita Facchetti (ORCID: https://orcid.org/0000-0003-1507-8073)
- Domenica Battaglia (ORCID: https://orcid.org/0000-0003-0491-4021)
- Carla Fornari (ORCID: https://orcid.org/0000-0002-9609-9556)
- Maria Luigia Gambardella (ORCID: https://orcid.org/0000-0002-4132-6221)
- Paolo Angelo Cortesi (ORCID: https://orcid.org/0000-0001-5241-4473)
- LG Mantovani (ORCID: https://orcid.org/0000-0003-3866-8199)
- Viola Doccini (ORCID: https://orcid.org/0000-0002-5166-8401)
- Marina Trivisano (ORCID: https://orcid.org/0000-0002-9841-8581)
- Simona Balestrini (ORCID: https://orcid.org/0000-0001-5639-1969)
- Alberto Cossu (ORCID: https://orcid.org/0000-0002-0766-7719)
- Nicola Specchio (ORCID: https://orcid.org/0000-0002-8120-0287)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Verona (IT)
- Meyer Children's Hospital (IT)
- Bambino Gesù Children's Hospital (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- University of the Sacred Heart (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Florence (IT)
- University of Milano-Bicocca (IT)
- KU Leuven (BE)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1002/epi4.70200
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00