Recurrent ischaemic strokes as a first presentation of Libman–Sacks endocarditis with an atypically massive mitral vegetation resulting in severe valvular regurgitation: a case report

The management of young individuals with ischaemic stroke should include attention to atypical causes. Libman-Sacks endocarditis is usually associated with small vegetations and high thrombotic risk, usually managed medically with anticoagulation and treatment of underlying conditions. Our case was atypical, with the presence of a large vegetation causing significant valvular dysfunction, but it demonstrates that replacement with mechanical prostheses can be a feasible management strategy.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-11-27
DOI
https://doi.org/10.1093/ehjcr/ytaf647
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Recurrent ischaemic strokes as a first presentation of Libman–Sacks endocarditis with an atypically massive mitral vegetation resulting in severe valvular regurgitation: a case report

Marco Spartera, Jan Lukas Robertus, Badrinathan Chandrasekaran, Pok‐Tin Tang et al.
European Heart Journal - Case Reports
Blood Coagulation and Thrombosis Mechanisms
article

Recurrent ischaemic strokes as a first presentation of Libman–Sacks endocarditis with an atypically massive mitral vegetation resulting in severe valvular regurgitation: a case report

Marco Spartera, Jan Lukas Robertus, Badrinathan Chandrasekaran, Pok‐Tin Tang, Steve Ramcharitar
article en

Abstract

The management of young individuals with ischaemic stroke should include attention to atypical causes. Libman-Sacks endocarditis is usually associated with small vegetations and high thrombotic risk, usually managed medically with anticoagulation and treatment of underlying conditions. Our case was atypical, with the presence of a large vegetation causing significant valvular dysfunction, but it demonstrates that replacement with mechanical prostheses can be a feasible management strategy.

European Heart Journal - Case ReportsVol. 9(12)
Great Western Hospital (GB), John Radcliffe Hospital (GB), Harefield Hospital (GB), University of Oxford (GB)
Openalex Percentile: Top 40%
Blood Coagulation and Thrombosis Mechanisms
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