Recurrent ischaemic strokes as a first presentation of Libman–Sacks endocarditis with an atypically massive mitral vegetation resulting in severe valvular regurgitation: a case report
The management of young individuals with ischaemic stroke should include attention to atypical causes. Libman-Sacks endocarditis is usually associated with small vegetations and high thrombotic risk, usually managed medically with anticoagulation and treatment of underlying conditions. Our case was atypical, with the presence of a large vegetation causing significant valvular dysfunction, but it demonstrates that replacement with mechanical prostheses can be a feasible management strategy.
Authors
- Marco Spartera (ORCID: https://orcid.org/0000-0002-8991-3396)
- Jan Lukas Robertus (ORCID: https://orcid.org/0000-0003-0433-7965)
- Badrinathan Chandrasekaran (ORCID: https://orcid.org/0000-0002-2265-0501)
- Pok‐Tin Tang (ORCID: https://orcid.org/0000-0003-2086-2743)
- Steve Ramcharitar
Institutions
- Great Western Hospital (GB)
- John Radcliffe Hospital (GB)
- Harefield Hospital (GB)
- University of Oxford (GB)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1093/ehjcr/ytaf647
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00