Clinical outcomes associated with ACE inhibitors and ARBs use in adults older than 85 years who recovered from dialysis‐requiring acute kidney injury

Among very old adults after dialysis for AKI, the ACEi/ARB therapy was significantly associated with lower risks of all-cause mortality and MAKE, but with a significantly increased risk of hypotension and hyperkalaemia. These findings support the cautious use of ACEi/ARB in this high-risk population.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2025-12-12
DOI
https://doi.org/10.1002/bcp.70408
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical outcomes associated with ACE inhibitors and ARBs use in adults older than 85 years who recovered from dialysis‐requiring acute kidney injury

Chung‐Yi Li, Jui‐Yi Chen
British Journal of Clinical Pharmacology
Acute Kidney Injury Research
article

Clinical outcomes associated with ACE inhibitors and ARBs use in adults older than 85 years who recovered from dialysis‐requiring acute kidney injury

Chung‐Yi Li, Jui‐Yi Chen
article en

Abstract

Among very old adults after dialysis for AKI, the ACEi/ARB therapy was significantly associated with lower risks of all-cause mortality and MAKE, but with a significantly increased risk of hypotension and hyperkalaemia. These findings support the cautious use of ACEi/ARB in this high-risk population.

British Journal of Clinical Pharmacology
Asia University (TW), China Medical University (TW), Ministry of Health and Welfare (TW), Chi Mei Medical Center (TW), Chia Nan University of Pharmacy and Science (TW), National Cheng Kung University (TW)
Openalex Percentile: Top 50%
Acute Kidney Injury Research
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