Upregulated Calcium Sensing Receptor Mediates Pulmonary Venous Remodeling in Pulmonary Hypertension
Upregulated CaSR mediating excessive PVSMCs proliferation through enhanced CaSR function and increased intracellular Ca<sup>2+</sup> signaling is an important pathogenic mechanism underlying the development of PVR in PH.
Authors
- Weitao Cao (ORCID: https://orcid.org/0000-0002-1113-603X)
- Yumin Zhou (ORCID: https://orcid.org/0000-0002-0555-8391)
- Zhenli Fu (ORCID: https://orcid.org/0000-0003-4246-2724)
- Gongyong Peng (ORCID: https://orcid.org/0000-0002-3187-3387)
- Qiudi Mo
- Xing Wen
- Shaoxing Li (ORCID: https://orcid.org/0009-0009-0866-3638)
- Luyao Wang (ORCID: https://orcid.org/0000-0003-1595-6593)
- Zhenbo Xu (ORCID: https://orcid.org/0000-0003-2865-2441)
- Wei Hong (ORCID: https://orcid.org/0000-0003-0265-5863)
- Gao Xiao-hua
- Hong Yuan (ORCID: https://orcid.org/0000-0003-4481-5298)
- Jiabi Liang (ORCID: https://orcid.org/0000-0001-7800-1853)
- Yan Xue
Institutions
- Zhengzhou University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou First People's Hospital (CN)
- Panyu District Central Hospital (CN)
- Henan Provincial Chest Hospital (CN)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1111/apha.70142
- Citations
- 1
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.52