Integrative bulk and single-cell transcriptomic profiling identifies core gene networks and potential therapeutic targets in glioma
The six identified hub genes are consistently downregulated in glioma and exhibit strong diagnostic potential. Their close association with the immune microenvironment and tumor-cell lineage highlights their value as biomarkers and potential therapeutic targets.
Authors
- Aijun Liang (ORCID: https://orcid.org/0000-0002-9429-4366)
- Jie Li (ORCID: https://orcid.org/0000-0001-5905-3359)
- Xingxing Jiang
- Yu Yang
- Yongping Gui
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1186/s12885-025-15454-5
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00