Maternal Folic Acid Supplement Use, Folate Intake, and Preterm Birth Among Infants With Spina Bifida
Our findings suggest a modestly elevated risk of preterm birth among infants with spina bifida born to women with the combination of no supplementation and low dietary folate intake. Future work confirming these findings and further investigating the timing of supplementation could help elucidate whether low folate intake is a risk factor for preterm birth in spina bifida-affected pregnancies.
Authors
- Suzan L. Carmichael (ORCID: https://orcid.org/0000-0001-6310-5924)
- Eva M. Williford (ORCID: https://orcid.org/0000-0003-3609-5665)
- Renata H. Benjamin (ORCID: https://orcid.org/0000-0001-6406-4247)
- Gary M. Shaw (ORCID: https://orcid.org/0000-0001-7438-4914)
- Tania A. Desrosiers (ORCID: https://orcid.org/0000-0003-1600-3700)
- A. J. Agopian (ORCID: https://orcid.org/0000-0002-5874-4155)
- Katherine L. Ludorf
- Jenil Patel (ORCID: https://orcid.org/0000-0002-4875-7390)
- Eirini Nestoridi
- Wendy N. Nembhard (ORCID: https://orcid.org/0000-0002-8318-4049)
- Rachel P. Allred (ORCID: https://orcid.org/0000-0003-0633-8013)
Institutions
- University of North Carolina at Chapel Hill (US)
- New York State Department of Health (US)
- Massachusetts Department of Public Health (US)
- Texas Department of State Health Services (US)
- University of Texas Health Science Center at Dallas (US)
- The University of Texas Health Science Center (US)
- University of Arkansas for Medical Sciences (US)
- The University of Texas Health Science Center at Houston (US)
- Stanford University (US)
Publication Details
- Journal
- Birth Defects Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/bdr2.70008
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00