Reverse vaccinology-based identification of immunogenic membrane proteins from zoonotic multidrug-resistant Proteus vulgaris: a one health approach to cross-species vaccine development

The study supports vaccine development as a viable strategy to combat multidrug-resistant P. vulgaris across species. The identified targets offer promising leads for developing species-specific or cross-protective vaccines applicable in veterinary and aquaculture settings. By addressing veterinary, aquaculture and zoonotic concerns, this research contributes to integrated "One Health" solutions for antimicrobial resistance control and cross-species disease prevention.