Long-term Persistence, Safety and Efficacy Profile of Dupilumab in Atopic Dermatitis: A Real-world Retrospective Multicenter Study From Spain

Dupilumab effectively reduced AD severity within the first few weeks, with most patients achieving mild/minimal disease activity or complete clearance by year 1. The observed safety profile was consistent with known data. High persistence rates up to 4-years suggest satisfaction with dupilumab long-term safety and efficacy profile in managing moderate-to-severe AD.

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Publication Details

Journal
Actas Dermo-Sifiliográficas
Published
2025-12-13
DOI
https://doi.org/10.1016/j.ad.2025.104563
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

Long-term Persistence, Safety and Efficacy Profile of Dupilumab in Atopic Dermatitis: A Real-world Retrospective Multicenter Study From Spain

Emilio Monte‐Boquet, Sergio Santos‐Alarcón, Rosa F. Ruiz de Apodaca, Joaquín Borrás‐Blasco et al.
Actas Dermo-Sifiliográficas
Dermatology and Skin Diseases
article

Long-term Persistence, Safety and Efficacy Profile of Dupilumab in Atopic Dermatitis: A Real-world Retrospective Multicenter Study From Spain

Emilio Monte‐Boquet, Sergio Santos‐Alarcón, Rosa F. Ruiz de Apodaca, Joaquín Borrás‐Blasco, F. J. Miquel, Nieves Prior, JF Silvestre, M.P. Ortega-García, V. Zaragoza, M. Rodriguez, A Mengual-Sendra
article en

Abstract

Dupilumab effectively reduced AD severity within the first few weeks, with most patients achieving mild/minimal disease activity or complete clearance by year 1. The observed safety profile was consistent with known data. High persistence rates up to 4-years suggest satisfaction with dupilumab long-term safety and efficacy profile in managing moderate-to-severe AD.

Actas Dermo-SifiliográficasVol. 117(4)
Hospital Universitari i Politècnic La Fe (ES), Hospital Arnau de Vilanova (ES), Hospital General Universitario De Valencia (ES), Hospital de Sagunto (ES), Hospital General Universitario de Alicante Doctor Balmis (ES), Hospital Virgen de los Lirios (ES)
Openalex Percentile: Top 37%
Dermatology and Skin Diseases
DOIOpen Access PDFOpenAlex
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Long-term Persistence, Safety and Efficacy Profile of Dupilumab in Atopic Dermatitis: A Real-world Retrospective Multicenter Study From Spain — Emilio Monte‐Boquet, Sergio Santos‐Alarcón, et al. · Actas Dermo-Sifiliográficas (2025) | TGRS Research Map | TGRS