Multi-factorial Hyperlactatemia Due to Linezolid and Metformin Treatment in the Setting of Vitamin C and B1 Deficiency

Although surgeons seek infection and sepsis to explain an elevated lactate, in a patient with multiple co-morbidities, medications, and risk factors such as vitamin deficiencies, a thorough analysis of their history and presentation is vital to uncovering the underlying causes(s) of lactic acidosis.

Authors

Harsh Patel (ORCID: https://orcid.org/0000-0003-0477-3126)
Stephen M. Kavic (ORCID: https://orcid.org/0000-0002-4278-6756)
Hugo Bonatti (ORCID: https://orcid.org/0000-0002-8591-4308)
Abdullah Amir
Amy VanderStoep
Anthony Iskarous

Institutions

University of Maryland, Baltimore (US)
American University of Antigua (AG)

Publication Details

Journal: Surgical Infections
Published: 2025-12-13
DOI: https://doi.org/10.1177/10962964251401522
Citations: 1
Primary Topic: Vitamin C and Antioxidants Research
Type: article
Field-Weighted Citation Impact: 1.12

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article

Multi-factorial Hyperlactatemia Due to Linezolid and Metformin Treatment in the Setting of Vitamin C and B1 Deficiency

Harsh Patel, Stephen M. Kavic, Hugo Bonatti, Abdullah Amir et al.

Dec 13, 2025

1 citations

Surgical Infections

Vitamin C and Antioxidants Research

1.12

article

Multi-factorial Hyperlactatemia Due to Linezolid and Metformin Treatment in the Setting of Vitamin C and B1 Deficiency

Harsh Patel, Stephen M. Kavic, Hugo Bonatti, Abdullah Amir, Amy VanderStoep, Anthony Iskarous

December 13, 2025article en

1 citations

Abstract

Although surgeons seek infection and sepsis to explain an elevated lactate, in a patient with multiple co-morbidities, medications, and risk factors such as vitamin deficiencies, a thorough analysis of their history and presentation is vital to uncovering the underlying causes(s) of lactic acidosis.

Surgical InfectionsVol. 27(2)

University of Maryland, Baltimore (US), American University of Antigua (AG)

Openalex Percentile: Top 17%

Vitamin C and Antioxidants Research

1.12

DOI Source OpenAlex

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