Hepatic CD4 T Cells Predict Hepatocellular Carcinoma Risk on Metabolic Dysfunction‐Associated Steatohepatitis Patients
Increase in liver CD4+ T cell infiltration characterizes MASH-to-HCC progression. These immune signatures combined with clinical parameters demonstrate remarkable predictive value for identifying high-risk MASH patients.
Authors
- André Boonstra (ORCID: https://orcid.org/0000-0001-8607-1616)
- Emilse Rodríguez (ORCID: https://orcid.org/0000-0002-4100-8506)
- Anna Lena Saborowski (ORCID: https://orcid.org/0000-0003-4857-4276)
- Patricia Calafat
- José D. Debes (ORCID: https://orcid.org/0000-0002-1512-2604)
- Sabrina Dhooge
- Pablo A. Romagnoli (ORCID: https://orcid.org/0000-0002-6328-9070)
- Nicolás Gonzalo Núñez (ORCID: https://orcid.org/0000-0003-3837-270X)
- Arndt Vogel (ORCID: https://orcid.org/0000-0003-0560-5538)
- Marina Fernandez (ORCID: https://orcid.org/0009-0002-7681-9058)
- Péter Simon
- María Kurpis
- Jhon Prieto (ORCID: https://orcid.org/0000-0002-8103-1989)
Institutions
- University of Minnesota (US)
- Universidad Nacional de Córdoba (AR)
- University of Toronto (CA)
- University of Minnesota System (US)
- Erasmus MC (NL)
- Medizinische Hochschule Hannover (DE)
- Research Centre in Biological Chemistry of Córdoba (AR)
- Centro Científico Tecnológico - Córdoba (AR)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Hospital Privado (AR)
Publication Details
- Journal
- United European Gastroenterology Journal
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1002/ueg2.70159
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission