Endoscopic Retrograde Cholangiopancreatography Combined with Percutaneous Drainage in Treating Disconnected Pancreatic Duct Syndrome

Disconnected pancreatic duct syndrome (DPDS), resulting from pancreatic injury or disease, is increasingly prevalent and poses significant challenges in clinical management due to its associated complications: leakage of pancreatic secretions, inflammation, and infection. DPDS is characterized by the leakage of pancreatic secretions into the surrounding tissues; this leakage often results from trauma, postoperative complications, or chronic pancreatitis. The resultant complications can significantly impair a patient's quality of life, necessitating effective and innovative treatment approaches. Although traditional management strategies for DPDS include surgical repair and conservative management, these strategies are often associated with high morbidity and complications. The limitations of these conventional approaches highlight the urgent need for alternative treatment modalities that reduce both surgical invasiveness and the risks associated with surgical repair. Endoscopic retrograde cholangiopancreatography (ERCP) is a well-established technique for diagnosing and treating conditions related to the biliary and pancreatic ducts. Given these challenges, exploring new diagnostic and therapeutic techniques is critical. Recent literature suggests that the combination of ERCP with percutaneous drainage (PCD) techniques may offer a promising alternative, potentially improving outcomes for patients suffering from DPDS. This study aims to investigate the efficacy and safety of ERCP combined with percutaneous drainage in the treatment of DPDS, providing novel insights into its clinical application.