Immunosuppressant use and adverse pregnancy outcomes in women with systemic lupus erythematosus: a retrospective cohort study in Korea

Continuity of hydroxychloroquine use from preconception through pregnancy reduces preterm birth risk in SLE. Conversely, early exposure to teratogenic immunosuppressants heightens the risk of spontaneous abortion. These findings underscore the importance of preconception medication planning in women with SLE.

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Publication Details

Journal
Lara D. Veeken
Published
2025-12-09
DOI
https://doi.org/10.1093/rheumatology/keaf651
Primary Topic
Pregnancy and Medication Impact
Type
article
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article

Immunosuppressant use and adverse pregnancy outcomes in women with systemic lupus erythematosus: a retrospective cohort study in Korea

Yeo‐Jin Song, Sun‐Young Jung, Yoon‐Kyoung Sung, Jong Hyuk Lee et al.
Lara D. Veeken
Pregnancy and Medication Impact
article

Immunosuppressant use and adverse pregnancy outcomes in women with systemic lupus erythematosus: a retrospective cohort study in Korea

Yeo‐Jin Song, Sun‐Young Jung, Yoon‐Kyoung Sung, Jong Hyuk Lee, Soo-Kyung Cho, Eun Jin Jang
article en

Abstract

Continuity of hydroxychloroquine use from preconception through pregnancy reduces preterm birth risk in SLE. Conversely, early exposure to teratogenic immunosuppressants heightens the risk of spontaneous abortion. These findings underscore the importance of preconception medication planning in women with SLE.

Lara D. VeekenVol. 65(2)
Gyeongguk National University (KR), Institute for Rheumatic Diseases (Japan) (JP), Hanyang University Seoul Hospital (KR), Hanyang University (KR), Chung-Ang University (KR)
Openalex Percentile: Top 49%
Pregnancy and Medication Impact
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Immunosuppressant use and adverse pregnancy outcomes in women with systemic lupus erythematosus: a retrospective cohort study in Korea — Yeo‐Jin Song, Sun‐Young Jung, et al. · Lara D. Veeken (2025) | TGRS Research Map | TGRS