Novel Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2) Inhibitors for Cancer Treatment
Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) is an enzyme that plays a critical role in regulating cell growth, development, and survival. This patent showcases the synthesis and pharmaceutical compositions of novel PTPN2 inhibitors and their applications in the prevention, treatment, and amelioration of cancers.
Authors
- Steven H. Liang (ORCID: https://orcid.org/0000-0003-1413-6315)
- Xin Mu Zhou (ORCID: https://orcid.org/0000-0002-1820-7830)
Institutions
- Emory University (US)
Publication Details
- Journal
- ACS Medicinal Chemistry Letters
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1021/acsmedchemlett.5c00692
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00