Single nucleotide variants in <i>VDR</i> and <i>GC</i> genes associated with osteoporosis in Mexican women
The GG genotype of rs2282679 seems to confer protection against osteoporosis. Further research, including functional validation and studies in larger and diverse cohorts, is warranted to elucidate the underlying biological mechanisms and confirm these results.
Authors
- María Eugenia Flores-Quijano (ORCID: https://orcid.org/0000-0002-8808-6739)
- Lucía López‐Rodríguez (ORCID: https://orcid.org/0000-0002-9153-0220)
- F. Germán Rodríguez-González (ORCID: https://orcid.org/0000-0002-8509-0804)
- Rosalba Sevilla‐Montoya (ORCID: https://orcid.org/0000-0002-5658-4661)
- Yuridia Martínez‐Meza (ORCID: https://orcid.org/0000-0002-7576-3841)
- Guillermo Federico Ortíz-Luna
- Angélica Castañeda-de-la-Fuente (ORCID: https://orcid.org/0000-0001-5503-5428)
- Alberto Hidalgo‐Bravo (ORCID: https://orcid.org/0000-0003-2506-8784)
- Liliana Fernández‐Hernández (ORCID: https://orcid.org/0000-0002-4153-6966)
- Héctor Borboa-Olivares (ORCID: https://orcid.org/0000-0001-7701-9621)
- Rafael Velázquez‐Cruz (ORCID: https://orcid.org/0000-0003-4515-0777)
- Mari Cruz Tolentino‐Dolores
- Luis Felipe León‐Madero (ORCID: https://orcid.org/0009-0006-1680-2691)
Institutions
- National Institute of Genetics (JP)
- Laboratory of Molecular Genetics (PL)
- Instituto Nacional de Perinatología (MX)
- National Institute of Genomic Medicine (MX)
- Instituto Nacional de Rehabilitación (MX)
- Institute of Genetics (HU)
Publication Details
- Journal
- Climacteric
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1080/13697137.2025.2584063
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00