The Effect of Febuxostat on Kidney Outcomes in Patients with Chronic Kidney Disease and Asymptomatic Hyperuricemia: A Target Trial Emulation

In patients with stage 3-4 CKD and asymptomatic hyperuricemia, initiation of febuxostat was not associated with kidney outcomes, all-cause mortality, or MACE. Further studies are warranted to validate these findings.

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Publication Details

Journal
American Journal of Nephrology
Published
2025-12-12
DOI
https://doi.org/10.1159/000550047
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00
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article

The Effect of Febuxostat on Kidney Outcomes in Patients with Chronic Kidney Disease and Asymptomatic Hyperuricemia: A Target Trial Emulation

Zihan Fang, Danna Zheng, Ran He, Bo Lin et al.
American Journal of Nephrology
Gout, Hyperuricemia, Uric Acid
article

The Effect of Febuxostat on Kidney Outcomes in Patients with Chronic Kidney Disease and Asymptomatic Hyperuricemia: A Target Trial Emulation

Zihan Fang, Danna Zheng, Ran He, Bo Lin, Tao Liu, Qi Liu
article en

Abstract

In patients with stage 3-4 CKD and asymptomatic hyperuricemia, initiation of febuxostat was not associated with kidney outcomes, all-cause mortality, or MACE. Further studies are warranted to validate these findings.

American Journal of Nephrology
Zhejiang Chinese Medical University (CN), Zhejiang Provincial People's Hospital (CN), Hangzhou Medical College (CN), Hangzhou City University
Openalex Percentile: Top 50%
Gout, Hyperuricemia, Uric Acid
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