Efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy or CAR-T cells for relapsed/refractory acute lymphoblastic leukemia: A multicenter phase ii trial

Adding PD-1 or PD-L1 blockade to either chemotherapy or CAR-T therapy improved clinical outcomes without excess toxicity in R/R ALL.

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Publication Details

Journal
Leukemia Research
Published
2025-12-12
DOI
https://doi.org/10.1016/j.leukres.2025.108148
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy or CAR-T cells for relapsed/refractory acute lymphoblastic leukemia: A multicenter phase ii trial

Bolin Wan, Min Zou, Jing Hu
Leukemia Research
CAR-T cell therapy research
article

Efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy or CAR-T cells for relapsed/refractory acute lymphoblastic leukemia: A multicenter phase ii trial

Bolin Wan, Min Zou, Jing Hu
article en

Abstract

Adding PD-1 or PD-L1 blockade to either chemotherapy or CAR-T therapy improved clinical outcomes without excess toxicity in R/R ALL.

Leukemia ResearchVol. 160
Ganzhou People's Hospital (CN)
Openalex Percentile: Top 44%
CAR-T cell therapy research
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Efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy or CAR-T cells for relapsed/refractory acute lymphoblastic leukemia: A multicenter phase ii trial — Bolin Wan, Min Zou, et al. · Leukemia Research (2025) | TGRS Research Map | TGRS