Stereotactic intracranial implantation of patient-derived glioblastoma cells in rats: A xenograft modeling approach
This method provides a reliable and translational platform that enhances the fidelity of preclinical GBM research. It offers an improved tool for drug evaluation and the development of personalized therapeutic strategies by more accurately mimicking the complex and heterogeneous nature of human GBM.
Authors
- Faezeh Yaghoubi
- Safieh Ebrahimi (ORCID: https://orcid.org/0000-0003-2135-867X)
- Ali Gorji (ORCID: https://orcid.org/0000-0002-4557-3270)
- Maryam Khaleghi Ghadiri (ORCID: https://orcid.org/0000-0002-7484-894X)
Institutions
- University of Münster (DE)
- Khatam University (IR)
Publication Details
- Journal
- Journal of Neuroscience Methods
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.jneumeth.2025.110658
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00