Future directions in viscoelastic hemostatic assay usage in bleeding patients
VHAs are valuable tools for bleeding management but remain limited by platform heterogeneity, incomplete assay specificity, and modest predictive accuracy. Future research should focus on assay standardization, dual platelet inhibition in fibrinogen assays, and improved discrimination of coagulation factor deficiencies to enable reliable, widely applicable clinical algorithms.
Authors
- Andreas Koster (ORCID: https://orcid.org/0000-0001-9713-6403)
- Gabor Erdoes (ORCID: https://orcid.org/0000-0002-6742-1016)
- Michael A. Mazzeffi (ORCID: https://orcid.org/0000-0003-2955-4915)
Institutions
- University of Bern (CH)
- University of Virginia Health System (US)
- University Hospital of Bern (CH)
- University of Virginia (US)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- Current Opinion in Anaesthesiology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1097/aco.0000000000001609
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00