Battle of the (Chat)Bots: Comparative Evaluation of April 2025 AI Model Accuracy on Pharmacotherapeutic Cases

Claude AI demonstrated the strongest overall performance. However, all tools exhibited limitations, reinforcing the need for clinical expert oversight. Though AI chatbots may support pharmacy education, our findings suggest that their current ability to perform multistep analysis remains limited. They often lack the clinical judgment, experience, and context needed for nuanced decision-making.