The use of methadone in cardiac surgery: resurgence of an old drug?
Further studies are needed to explore the mechanisms and ideal protocols for incorporating methadone into routine use as part of existing enhanced recover protocols. Long-term treatment effects extending beyond the immediate postoperative period, outcomes when included with adjuncts, and broader dose-response analysis are needed to guide future implementation.
Authors
- Joseph Walpole (ORCID: https://orcid.org/0000-0003-4174-8886)
- Adam J. Milam (ORCID: https://orcid.org/0000-0001-9306-1598)
- Jessica L. Barnes
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Mayo Clinic Hospital (US)
Publication Details
- Journal
- Current Opinion in Anaesthesiology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1097/aco.0000000000001600
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00