Dendritic fibromyxolipoma of the male breast: case report and literary review

DFML is a benign lipomatous tumor with unique morphological features. Complete surgical excision typically leads to no recurrence. This report documents the first known instance of DFML in the mammary gland of a male patient. Furthermore, an analysis of 95 previously documented cases of DFML was conducted. It is strongly advocated that the World Health Organization reclassify DFML as a mucinous subtype of spindle cell lipoma. This reclassification would improve the understanding of DFML and help avoid unnecessary aggressive treatments due to misdiagnosis as a malignancy.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-12-12
DOI
https://doi.org/10.3389/fmed.2025.1653754
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Dendritic fibromyxolipoma of the male breast: case report and literary review

Shuai Luo, Di Wu, Xiaoxue Tian, Ting Xu et al.
Frontiers in Medicine
Cancer and Skin Lesions
article

Dendritic fibromyxolipoma of the male breast: case report and literary review

Shuai Luo, Di Wu, Xiaoxue Tian, Ting Xu, Jinjing Wang, Xiaolan Li, Q Y Ge
article en

Abstract

DFML is a benign lipomatous tumor with unique morphological features. Complete surgical excision typically leads to no recurrence. This report documents the first known instance of DFML in the mammary gland of a male patient. Furthermore, an analysis of 95 previously documented cases of DFML was conducted. It is strongly advocated that the World Health Organization reclassify DFML as a mucinous subtype of spindle cell lipoma. This reclassification would improve the understanding of DFML and help avoid unnecessary aggressive treatments due to misdiagnosis as a malignancy.

Frontiers in MedicineVol. 12
Guiyang Medical University (CN), Zunyi Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN)
Openalex Percentile: Top 37%
Cancer and Skin Lesions
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Dendritic fibromyxolipoma of the male breast: case report and literary review — Shuai Luo, Di Wu, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS