LINC00659 regulates HSP90-IKKα interaction to activate NF-κB signaling and promote glioma invasion

This study identified LINC00659 as a key promoter of glioma cell migration, invasion, and EMT, suggesting its potential as a target against glioma malignancy.

Authors

Hui Dong (ORCID: https://orcid.org/0000-0002-2244-2040)
Lijuan Du (ORCID: https://orcid.org/0000-0001-6792-3684)
Tao Lin (ORCID: https://orcid.org/0009-0008-6718-5317)
Shanshan Cai (ORCID: https://orcid.org/0000-0002-0594-0953)

Institutions

Punan Hospital (CN)

Publication Details

Journal: Neurological Research
Published: 2025-12-12
DOI: https://doi.org/10.1080/01616412.2025.2594599
Primary Topic: Heat shock proteins research
Type: article
Field-Weighted Citation Impact: 0.00

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article

LINC00659 regulates HSP90-IKKα interaction to activate NF-κB signaling and promote glioma invasion

Hui Dong, Lijuan Du, Tao Lin, Shanshan Cai

Dec 12, 2025

Neurological Research

Heat shock proteins research

article

LINC00659 regulates HSP90-IKKα interaction to activate NF-κB signaling and promote glioma invasion

Hui Dong, Lijuan Du, Tao Lin, Shanshan Cai

December 12, 2025article en

Abstract

This study identified LINC00659 as a key promoter of glioma cell migration, invasion, and EMT, suggesting its potential as a target against glioma malignancy.

Neurological Research

Punan Hospital (CN)

Openalex Percentile: Top 64%

Heat shock proteins research

DOI Source OpenAlex

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LINC00659 regulates HSP90-IKKα interaction to activate NF-κB signaling and promote glioma invasion — Hui Dong, Lijuan Du, et al. · Neurological Research (2025) | TGRS Research Map | TGRS