Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluids Improves Pathogen Detection and Antimicrobial Stewardship in Lower Respiratory Tract Infections: A Retrospective Study
mNGS is an effective tool for diagnosing LRTIs, with significantly higher pathogen detection rates than traditional methods. mNGS also demonstrates high accuracy in predicting antimicrobial resistance, providing crucial support for clinical treatment decisions.
Authors
- Ju Cao (ORCID: https://orcid.org/0000-0002-4855-6986)
- Yun Xia (ORCID: https://orcid.org/0000-0003-3136-8548)
- Qinqin Zhang (ORCID: https://orcid.org/0000-0003-3629-1914)
- Xiuyu Xu
- Xuelian Ji
- Xiangsong Ma
Institutions
- People's Hospital of Bishan District (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s572028
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China