Fasting urine osmolality and risk of kidney disease progression in patients with type 2 diabetes

Low level of fasting urine osmolality is associated with increased risk of kidney disease progression independent of conventional risk factors. This readily accessible biomarker may potentially improve risk-stratification for patients with type 2 diabetes.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2025-12-11
DOI
https://doi.org/10.1093/ndt/gfaf264
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
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article

Fasting urine osmolality and risk of kidney disease progression in patients with type 2 diabetes

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Nephrology Dialysis Transplantation
Chronic Kidney Disease and Diabetes
article

Fasting urine osmolality and risk of kidney disease progression in patients with type 2 diabetes

Joe De Keizer, Huili Zheng, Keven Ang, Pierre‐Jean Saulnier, Bryan Kestenbaum, Vincent Javaugue, Jian-Jun Liu, Petter Bjornstad, Janus Lee, Resham L Gurung, Louis Potier, Robert G. Nelson, Su Chi Lim, Samy Hadjadj, Sylvia Liu
article en

Abstract

Low level of fasting urine osmolality is associated with increased risk of kidney disease progression independent of conventional risk factors. This readily accessible biomarker may potentially improve risk-stratification for patients with type 2 diabetes.

Nephrology Dialysis Transplantation
Joslin Diabetes Center (US), Centre National de la Recherche Scientifique (FR), Inserm (FR), National University of Singapore (SG), Nanyang Technological University (SG), University of Washington (US), Université Paris Cité (FR), Kidney Research UK (GB), Khoo Teck Puat Hospital (SG), Université de Poitiers (FR), Institut Necker Enfants Malades (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier Universitaire de Poitiers (FR), Duke-NUS Medical School (SG), Contrôle de la Réponse Immune B et Lymphoproliférations (FR), Institut du Thorax (FR), Hôpital Bichat-Claude-Bernard (FR), National University Health System (SG), Institute of Nutrition, Metabolism and Diabetes (CA), Nantes Université (FR)
Openalex Percentile: Top 50%
Chronic Kidney Disease and Diabetes
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