Reactive Infectious Mucocutaneous Eruption: A Case Series

Erythema multiforme is an acute immunologically mediated condition that presents with mucocutaneous lesions. The term reactive infectious mucocutaneous eruption (RIME) has recently been used to describe mucocutaneous eruptions following respiratory infection. RIME is reported most frequently in children and adolescents, and generally presents with involvement of the mucous membranes, particularly the oral mucosa, with minimal or no skin involvement. This article presents four paediatric patients who presented with mucocutaneous eruptions to the Royal Hospital for Children, Glasgow, and the Royal Hospital for Children and Young People, Edinburgh, over a 5-month period, with discussion regarding the management of such patients. CPD/Clinical Relevance: Many patients with erythema multiforme have oral lesions and may seek advice from their general dental practitioner.

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Journal
Dental Update
Published
2025-12-02
DOI
https://doi.org/10.12968/denu.2025.52.11.822
Primary Topic
Drug-Induced Adverse Reactions
Type
article
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article

Reactive Infectious Mucocutaneous Eruption: A Case Series

Aoife Crummey, Robert JR Reilly, Alex Crighton, L. E. Cross
Dental Update
Drug-Induced Adverse Reactions
article

Reactive Infectious Mucocutaneous Eruption: A Case Series

Aoife Crummey, Robert JR Reilly, Alex Crighton, L. E. Cross
article en

Abstract

Erythema multiforme is an acute immunologically mediated condition that presents with mucocutaneous lesions. The term reactive infectious mucocutaneous eruption (RIME) has recently been used to describe mucocutaneous eruptions following respiratory infection. RIME is reported most frequently in children and adolescents, and generally presents with involvement of the mucous membranes, particularly the oral mucosa, with minimal or no skin involvement. This article presents four paediatric patients who presented with mucocutaneous eruptions to the Royal Hospital for Children, Glasgow, and the Royal Hospital for Children and Young People, Edinburgh, over a 5-month period, with discussion regarding the management of such patients. CPD/Clinical Relevance: Many patients with erythema multiforme have oral lesions and may seek advice from their general dental practitioner.

Dental UpdateVol. 52(11)
NHS Lothian (GB), NHS Greater Glasgow and Clyde (GB), Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
Openalex Percentile: Top 57%
Drug-Induced Adverse Reactions
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