Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis
To our knowledge, our research provides evidence for the feasibility of ethologically valid burrowing behaviour as a non-invasive predictor of EM incidence in the syngeneic mice model. Future preclinical drug research for EM management could leverage BA to identify and select only lesion-positive animals for intervention trials. This approach will enhance the translational value of EM research.
Authors
- Krishnadas Nandakumar (ORCID: https://orcid.org/0000-0001-6653-4660)
- Rooma Sinha (ORCID: https://orcid.org/0000-0001-8221-2282)
- Samruddhi Deshpande
- Jayesh Mudgal (ORCID: https://orcid.org/0000-0001-8190-7031)
- Rahul Dutta (ORCID: https://orcid.org/0000-0003-2918-9591)
- Megha M Anchan
- Atharvaraj Hande
Institutions
- Manipal Academy of Higher Education (IN)
- Apollo Hospitals (IN)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12905-025-04112-4
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70