Safety and efficacy of a feed additive consisting of alpha‐galactosidase (produced with Aspergillus tubingensis ATCC SD 6740) and endo‐1,4‐beta‐xylanase (produced with Trichoderma orientale CBS 139997) (Capsozyme SB Plus) for turkeys for fattening an
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a preparation containing alpha-galactosidase (EC 3.2.1.22) and endo-1,4-beta-xylanase (EC 3.2.1.8) (Capsozyme SB Plus) as a zootechnical feed additive (functional group: digestibility enhancers). The additive is already authorised for use in feed for chickens for fattening, chickens reared for laying, minor poultry species for fattening and reared for laying and ornamental birds. The applicant is seeking an extension of use to turkeys for fattening and reared for breeding at the minimum inclusion level of 14 alpha-galactosidase activity units (GALU) and 18 endo-1,4-beta-xylanase activity units (AXC) per kg of complete feed and a maximum inclusion level of 20 GALU and 25 AXC units per kg of complete feed. Based on the results observed in a tolerance trial in chickens for fattening that had been previously evaluated, the FEEDAP Panel concluded that Capsozyme SB Plus is safe for turkeys for fattening and reared for breeding at the maximum recommended level of 20 GALU and 25 AXC units per kg complete feed. The use of the feed additive in turkeys for fattening and reared for breeding under the proposed conditions of use is considered safe for consumers and the environment. Regarding safety for the user, Capsozyme SB Plus is considered a respiratory sensitiser and exposure by inhalation is considered a risk. No conclusions could be reached on the potential of the additive to be irritant to the skin or eyes or a skin sensitiser. Capsozyme SB Plus is considered to be efficacious in turkeys for fattening and reared for laying at the proposed minimum use level of 14 GALU and 18 AXC units per kg complete feed.
Authors
- Ilen Röhe
- Paul Brantom
- Alena Pechová (ORCID: https://orcid.org/0000-0002-3798-1899)
- Eleftherios Bonos (ORCID: https://orcid.org/0000-0002-8166-564X)
- Henrik Christensen (ORCID: https://orcid.org/0000-0003-4238-4658)
- Roberto Edoardo Villa (ORCID: https://orcid.org/0000-0001-5536-1370)
- Katerina Theodoridou (ORCID: https://orcid.org/0000-0002-2848-5594)
- Marta López‐Alonso (ORCID: https://orcid.org/0000-0001-6426-4273)
- Francesca Marcon (ORCID: https://orcid.org/0000-0002-0431-8310)
- Ronette Gehring (ORCID: https://orcid.org/0000-0002-1329-201X)
- Carlo Nebbia (ORCID: https://orcid.org/0000-0003-0624-7787)
- Miguel Prieto Maradona (ORCID: https://orcid.org/0000-0001-9202-3856)
- Matteo Lorenzo Innocenti
- Mojca Durjava
- Maryline Kouba
- Boet Glandorf (ORCID: https://orcid.org/0000-0003-3743-5107)
- Rosella Brozzi
- Giovanna Azimonti
- Elisa Pettenati
- Birgit Dusemund
- Montserrat Anguita
- Jaume Galobart
- Fabiola Pizzo
Publication Details
- Journal
- EFSA Journal
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2903/j.efsa.2025.9796
- Citations
- 1
- Primary Topic
- Agricultural safety and regulations
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- European Food Safety Authority