Multimodal analysis reveals potential association of CDH13 with endothelial cells and its overexpression in hepatocellular carcinoma
CDH13 is highly expressed in HCC and may promote angiogenesis, immune evasion, and metabolic reprogramming via the FOXA1-CDH13 axis, suggesting its potential as a therapeutic target.
Authors
- Rong‐Quan He (ORCID: https://orcid.org/0000-0002-7752-2080)
- Diyuan Qin
- Xiaobo Jiang (ORCID: https://orcid.org/0009-0000-7421-9193)
- Jian‐Di Li (ORCID: https://orcid.org/0000-0001-7050-371X)
- Yi‐Wu Dang (ORCID: https://orcid.org/0000-0002-7793-1239)
- Ke-Jun Wu (ORCID: https://orcid.org/0009-0007-9017-6382)
- Han He
- Lu Zhang (ORCID: https://orcid.org/0000-0001-8358-6112)
- Gang Chen (ORCID: https://orcid.org/0000-0002-8320-6594)
- Mingjie Li (ORCID: https://orcid.org/0000-0002-6211-3575)
- Jianjun Li (ORCID: https://orcid.org/0000-0002-2842-5663)
- Dongming Li
- Lihua Yang (ORCID: https://orcid.org/0009-0004-5330-7070)
- Qi Li (ORCID: https://orcid.org/0000-0001-5938-0173)
- Shi-De Li
- Jifeng He
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s40001-025-03667-0
- Primary Topic
- FOXO transcription factor regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00