Piezo1-mediated neuroexcitation via collaboration with KCa1.1 and Nav1.9 currents in myelinated Ah-type of trigeminal ganglion neurons in rats: Mechanistic insights with sex-specific effects
These datasets have demonstrated Piezo1-mediated neuroexcitation of female-specific subpopulation of myelinated Ah-type TG neurons due at least to the coupling between N-type Ca<sup>2+</sup> channel and KCa1.1 and functional upregulation of Nav1.9, which uncovers an additional insights for higher incidence of migraine in woman.
Authors
- Yao Song (ORCID: https://orcid.org/0000-0003-1699-759X)
- Xingye Ren (ORCID: https://orcid.org/0009-0006-6442-4226)
- Dapeng Ding (ORCID: https://orcid.org/0000-0003-0175-6902)
- Shuangshuang Liu (ORCID: https://orcid.org/0000-0002-8949-1437)
- Yang Liu (ORCID: https://orcid.org/0000-0002-0367-8189)
- Meng Li (ORCID: https://orcid.org/0000-0002-9936-8563)
- Zixuan Li (ORCID: https://orcid.org/0009-0000-9617-3982)
- Xiao‐Long Lu (ORCID: https://orcid.org/0009-0005-6484-3095)
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Affiliated Zhongshan Hospital of Dalian University (CN)
Publication Details
- Journal
- Molecular Pain
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1177/17448069251410754
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00