Neoadjuvant Immunotherapy With Prolgolimab in Patients With Locally Advanced Microsatellite Instability/Defective Mismatch Repair Colorectal Cancer

The use of prolgolimab in locally advanced dMMR/MSI CRC is associated with high rates of pCR and cCR, allowing for further exploration of organ-sparing approaches in these patients.

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Publication Details

Journal
JCO Precision Oncology
Published
2025-12-01
DOI
https://doi.org/10.1200/po-25-00602
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Neoadjuvant Immunotherapy With Prolgolimab in Patients With Locally Advanced Microsatellite Instability/Defective Mismatch Repair Colorectal Cancer

В. А. Алиев, З. З. Мамедли, А. М. Строганова, Khasan Dzhumabaev et al.
JCO Precision Oncology
Genetic factors in colorectal cancer
article

Neoadjuvant Immunotherapy With Prolgolimab in Patients With Locally Advanced Microsatellite Instability/Defective Mismatch Repair Colorectal Cancer

В. А. Алиев, З. З. Мамедли, А. М. Строганова, Khasan Dzhumabaev, A. V. Polynovskiy, N. Ts. Drobot, Olesya Kuznetsova, A. A. Zagidullina, A. Tryakin, А. А. Анискин, И. А. Карасев, М. Yu. Fedyanin, Maxim Ivanov, Aleksander Prokopiev
article en

Abstract

The use of prolgolimab in locally advanced dMMR/MSI CRC is associated with high rates of pCR and cCR, allowing for further exploration of organ-sparing approaches in these patients.

JCO Precision OncologyVol. 9(9)
Sechenov University (RU), Moscow Clinical Scientific Center (RU), Scientific Research Institute of Healthcare Organization and Medical Management (RU), National Medical Research Center of Cardiology (RU), Moscow City Oncology Hospital №62 (RU)
Openalex Percentile: Top 44%
Genetic factors in colorectal cancer
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Neoadjuvant Immunotherapy With Prolgolimab in Patients With Locally Advanced Microsatellite Instability/Defective Mismatch Repair Colorectal Cancer — В. А. Алиев, З. З. Мамедли, et al. · JCO Precision Oncology (2025) | TGRS Research Map | TGRS