OCT-based retinal biomarkers forecast central nervous system structural decline in Parkinson’s disease: A longitudinal multimodal study within the Persian Cohort

Retinal alterations in PD are closely aligned with concurrent brain neurodegeneration and may serve as predictive biomarkers. These findings suggest that OCT, when combined with MRI, may support a non-invasive strategy for early risk stratification and longitudinal monitoring of PD.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-12-08
DOI
https://doi.org/10.1016/j.pdpdt.2025.105310
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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OCT
article

OCT-based retinal biomarkers forecast central nervous system structural decline in Parkinson’s disease: A longitudinal multimodal study within the Persian Cohort

Zohreh Ganji, Nasser Shoeibi, Ali Shoeibi, Hoda Zare et al.
Photodiagnosis and Photodynamic Therapy
Parkinson's Disease Mechanisms and Treatments
article

OCT-based retinal biomarkers forecast central nervous system structural decline in Parkinson’s disease: A longitudinal multimodal study within the Persian Cohort

Zohreh Ganji, Nasser Shoeibi, Ali Shoeibi, Hoda Zare, Farzane Nikparast, Nooshin Akbari-Sharak
article en

Abstract

Retinal alterations in PD are closely aligned with concurrent brain neurodegeneration and may serve as predictive biomarkers. These findings suggest that OCT, when combined with MRI, may support a non-invasive strategy for early risk stratification and longitudinal monitoring of PD.

Photodiagnosis and Photodynamic TherapyVol. 57
Mashhad University of Medical Sciences (IR)
Openalex Percentile: Top 45%
Parkinson's Disease Mechanisms and Treatments
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