Mechanisms of Suanzaoren () and its processed products in treating insomnia: an integrated study based on network pharmacology and metabolomics.
Combining <i>in vivo</i> experiments, metabolomics, and network pharmacology, we have identified potential pharmacological mechanisms by which ZSS and its derivatives mitigate insomnia. These findings provide a theoretical foundation for the further development and utilization of ZSS, supporting the innovation of new therapeutic agents for insomnia treatment.
Authors
- Ji Shi (ORCID: https://orcid.org/0000-0002-6409-4662)
- Jia Tian-zhu (ORCID: https://orcid.org/0000-0001-6750-2134)
- Hua Yue (ORCID: https://orcid.org/0000-0003-2621-8326)
- Jing Lian (ORCID: https://orcid.org/0000-0001-9753-1980)
- S U Guoming
- Yuan Zhang (ORCID: https://orcid.org/0000-0002-1624-3715)
- Pengpeng Liu (ORCID: https://orcid.org/0000-0001-6515-4682)
- Chao Zhang (ORCID: https://orcid.org/0000-0001-9533-3737)
- Cheng Shizan
Institutions
- Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2025.06.010
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00