Post-Caustic Esophagitis: Updated Clinical Insights and Practical Lessons from Case Illustrations
<b>Background:</b> Caustic ingestion represents a severe clinical emergency, leading to variable and often unpredictable outcomes. The severity depends on the nature of the corrosive agent, the amount ingested, and the timing of management. <b>Summary:</b> This review provides an updated overview of post-caustic esophagitis, integrating epidemiology, pathophysiology, clinical spectrum, diagnostic strategies, and management principles. Special emphasis is placed on complications such as strictures, fistulas, and long-term nutritional consequences. To illustrate practical aspects, we present two recent cases managed in our department, reflecting the contrasting patterns of acid and alkali injury. A brief reference to our previously published retrospective analysis of 188 patients referred to Clinical Emergency Hospital of Bucharest between January 2003-January 2004 complements this clinical perspective. <b>Conclusions:</b> Post-caustic esophagitis remains a major therapeutic challenge. Early endoscopic assessment, individualized management, and multidisciplinary follow-up are crucial to improving patient outcomes. Preventive strategies and public education are equally essential to reduce the incidence of this life-threatening condition.
Authors
- Ruxandra Opriţă
- Bogdan Dinu (ORCID: https://orcid.org/0009-0006-8597-9167)
- Bogdan Opriță
- Alice Elena Diaconu (ORCID: https://orcid.org/0009-0009-4157-6421)
- Anca Arina Ghiorghiu
Institutions
- Carol Davila University of Medicine and Pharmacy (RO)
- Clinical Emergency Hospital Bucharest (RO)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3390/jcm14238575
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00