Post-Caustic Esophagitis: Updated Clinical Insights and Practical Lessons from Case Illustrations

<b>Background:</b> Caustic ingestion represents a severe clinical emergency, leading to variable and often unpredictable outcomes. The severity depends on the nature of the corrosive agent, the amount ingested, and the timing of management. <b>Summary:</b> This review provides an updated overview of post-caustic esophagitis, integrating epidemiology, pathophysiology, clinical spectrum, diagnostic strategies, and management principles. Special emphasis is placed on complications such as strictures, fistulas, and long-term nutritional consequences. To illustrate practical aspects, we present two recent cases managed in our department, reflecting the contrasting patterns of acid and alkali injury. A brief reference to our previously published retrospective analysis of 188 patients referred to Clinical Emergency Hospital of Bucharest between January 2003-January 2004 complements this clinical perspective. <b>Conclusions:</b> Post-caustic esophagitis remains a major therapeutic challenge. Early endoscopic assessment, individualized management, and multidisciplinary follow-up are crucial to improving patient outcomes. Preventive strategies and public education are equally essential to reduce the incidence of this life-threatening condition.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-12-03
DOI
https://doi.org/10.3390/jcm14238575
Primary Topic
Esophageal and GI Pathology
Type
article
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article

Post-Caustic Esophagitis: Updated Clinical Insights and Practical Lessons from Case Illustrations

Ruxandra Opriţă, Bogdan Dinu, Bogdan Opriță, Alice Elena Diaconu et al.
Journal of Clinical Medicine
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article

Post-Caustic Esophagitis: Updated Clinical Insights and Practical Lessons from Case Illustrations

Ruxandra Opriţă, Bogdan Dinu, Bogdan Opriță, Alice Elena Diaconu, Anca Arina Ghiorghiu
article en

Abstract

<b>Background:</b> Caustic ingestion represents a severe clinical emergency, leading to variable and often unpredictable outcomes. The severity depends on the nature of the corrosive agent, the amount ingested, and the timing of management. <b>Summary:</b> This review provides an updated overview of post-caustic esophagitis, integrating epidemiology, pathophysiology, clinical spectrum, diagnostic strategies, and management principles. Special emphasis is placed on complications such as strictures, fistulas, and long-term nutritional consequences. To illustrate practical aspects, we present two recent cases managed in our department, reflecting the contrasting patterns of acid and alkali injury. A brief reference to our previously published retrospective analysis of 188 patients referred to Clinical Emergency Hospital of Bucharest between January 2003-January 2004 complements this clinical perspective. <b>Conclusions:</b> Post-caustic esophagitis remains a major therapeutic challenge. Early endoscopic assessment, individualized management, and multidisciplinary follow-up are crucial to improving patient outcomes. Preventive strategies and public education are equally essential to reduce the incidence of this life-threatening condition.

Journal of Clinical MedicineVol. 14(23)
Carol Davila University of Medicine and Pharmacy (RO), Clinical Emergency Hospital Bucharest (RO)
Openalex Percentile: Top 40%
Esophageal and GI Pathology
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