Wenshen Zhuanggu Fang reduces breast cancer bone metastasis by regulating macrophage polarization: a bioinformatics analysis combined with experimental validation.
WSZG inhibited breast cancer bone metastasis by adjusting the promoting effect of macrophages on MDA-MB-231BO breast cancer cells and decreasing M2 polarization by downregulating STAT signaling.
Authors
- Qiong Li (ORCID: https://orcid.org/0000-0001-5936-7059)
- Sheng Liu (ORCID: https://orcid.org/0000-0001-5119-0324)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-1317-120X)
- Yi Wang (ORCID: https://orcid.org/0000-0003-4848-131X)
- Xiaofei Liu (ORCID: https://orcid.org/0000-0003-4379-4923)
- Xiaojuan Yang (ORCID: https://orcid.org/0000-0002-5789-7571)
- Shi Youyang
- Rui Yang (ORCID: https://orcid.org/0000-0002-2036-0156)
- Xianghui Han (ORCID: https://orcid.org/0000-0002-1285-3284)
- Liu Feifei
- Sun Chenping
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2025.06.009
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00