Transdermal diclofenac versus oral paracetamol-ibuprofen combination for postoperative pain following surgical extraction of mandibular third molar: a randomized controlled trial
Both the transdermal diclofenac patch and the oral combination of paracetamol and ibuprofen are effective in managing postoperative pain following mandibular third molar extraction. However, the transdermal diclofenac patch has significantly fewer gastrointestinal side effects, making it a preferable option for patients at risk of gastric irritation.
Authors
- Siddhartha Rai (ORCID: https://orcid.org/0000-0002-7815-657X)
- Mehul Rajesh Jaisani
- Ashok Dongol (ORCID: https://orcid.org/0000-0002-8664-6376)
- Bibek Kattel (ORCID: https://orcid.org/0000-0002-6290-2654)
- Asish Subedi (ORCID: https://orcid.org/0000-0002-0471-8760)
- Pradeep Acharya (ORCID: https://orcid.org/0000-0001-5358-4079)
- Anjani Kumar Yadav (ORCID: https://orcid.org/0000-0002-9734-3688)
- Niroj Khanal (ORCID: https://orcid.org/0009-0004-6851-5569)
Institutions
- B.P. Koirala Institute of Health Sciences (NP)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1097/ms9.0000000000004076
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00