Dental Manifestations and Clinical Implications of Diamond-Blackfan Anemia.

Diamond-Blackfan anemia is a rare inherited bone marrow failure syndrome. It is part of a group of genetic disorders characterized by a decrease in red blood cells due to bone marrow malfunction. It affects five to seven live births per million per year. Pediatric patients are typically diagnosed within the first year of life; however, clinical manifestations can present at any age. Advances in molecular testing have increased the ability to identify Diamond-Blackfan anemia variants in adults. Patients with the disease have a wide range of features, including distinct physical characteristics; however, there is limited literature highlighting the dental manifestations and implications of the disease. Therefore, the purpose of this case report is to review the literature on Diamond-Blackfan anemia and highlight the unique challenges that dental practitioners may face in the delivery of dental care.