Effect of Xuanfei Tongqiao acupuncture on nasal inflammation in rats with allergic rhinitis: modulation of long non-coding RNA growth arrest-specific transcript 5 methylation modification.
Xuanfei Tongqiao acupuncture therapy inhibited the METTL3-GAS5-GATA3-IL-33-ILC2 pathway, reducing the inflammatory response and alleviating nasal symptoms in AR rats. These results suggest that Xuanfei Tongqiao acupuncture could serve as a potential alternative therapy for preventing and managing AR associated with inflammation.
Authors
- Yongjun Peng (ORCID: https://orcid.org/0000-0003-0851-7795)
- Yang Chen (ORCID: https://orcid.org/0009-0008-9837-8613)
- Yan Shen (ORCID: https://orcid.org/0000-0002-2590-8985)
- Lyu Hequn
- Zeng Chunli
- Zhang Hanrui
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2025.06.007
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00