Analysis of gut microbiota in Restless Legs Syndrome: searching for a metagenomic signature
Although only a few previous studies have reported the presence of small intestinal bacterial overgrowth (SIBO) in RLS, to the best of our knowledge this is the first study to highlight significant differences in the gut microbiota composition of RLS compared to both CTRL and INS, identifying a specific RLS metagenomic signature.
Authors
- Giuseppe Loddo (ORCID: https://orcid.org/0000-0001-8748-5984)
- Chiara Pirazzini (ORCID: https://orcid.org/0000-0001-8248-0295)
- Elena Mazzotta (ORCID: https://orcid.org/0009-0001-6906-2168)
- Greta Mainieri (ORCID: https://orcid.org/0000-0002-6159-854X)
- Maria Giulia Bacalini (ORCID: https://orcid.org/0000-0003-1618-2673)
- Claudia Sala (ORCID: https://orcid.org/0000-0002-4889-1047)
- Angelica Montini (ORCID: https://orcid.org/0000-0001-5625-8850)
- Camilla Pellegrini (ORCID: https://orcid.org/0000-0003-2636-477X)
- Sara De Fanti (ORCID: https://orcid.org/0000-0001-5482-8215)
- Francesco Carano
- Federica Provini (ORCID: https://orcid.org/0000-0001-9063-2658)
- Francesco Ravaioli (ORCID: https://orcid.org/0000-0001-6976-8489)
- Luca Baldelli (ORCID: https://orcid.org/0000-0003-3666-1735)
Institutions
- GNA University (IN)
- Azienda USL di Bologna (IT)
- Istituto Ortopedico Rizzoli (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- University of Bologna (IT)
Publication Details
- Journal
- SLEEP
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1093/sleep/zsaf383
- Citations
- 1
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35