Predictive value of elevated interleukin-33 levels for multi-organ dysfunction syndrome in trauma patients in South Korea: a prospective observational study

The findings suggest that initial IL-33 levels are elevated in the MODS group, compared with non-MODS group, and exhibit a rapidly declining trend, showing an initial association with MODS that was not maintained in a multivariate analysis. These findings suggest that IL-33 might have relevance in assessing trauma severity; however, further validation is required before it can be considered a biomarker for MODS.

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Publication Details

Journal
Acute and Critical Care
Published
2025-11-28
DOI
https://doi.org/10.4266/acc.002500
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Predictive value of elevated interleukin-33 levels for multi-organ dysfunction syndrome in trauma patients in South Korea: a prospective observational study

Md Habibur Rahman, Myoung Jun Kim, Sang‐Hyun An, Cheol-Su Kim et al.
Acute and Critical Care
IL-33, ST2, and ILC Pathways
article

Predictive value of elevated interleukin-33 levels for multi-organ dysfunction syndrome in trauma patients in South Korea: a prospective observational study

Md Habibur Rahman, Myoung Jun Kim, Sang‐Hyun An, Cheol-Su Kim, In Sik Shin, Da Kyung Kim, Kwangmin Kim
article en

Abstract

The findings suggest that initial IL-33 levels are elevated in the MODS group, compared with non-MODS group, and exhibit a rapidly declining trend, showing an initial association with MODS that was not maintained in a multivariate analysis. These findings suggest that IL-33 might have relevance in assessing trauma severity; however, further validation is required before it can be considered a biomarker for MODS.

Acute and Critical CareVol. 40(4)
Yonsei University (KR), Wonju Severance Christian Hospital (KR), Armed Forces Capital Hospital (KR)
Openalex Percentile: Top 54%
IL-33, ST2, and ILC Pathways
DOIOpen Access PDFOpenAlex
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Predictive value of elevated interleukin-33 levels for multi-organ dysfunction syndrome in trauma patients in South Korea: a prospective observational study — Md Habibur Rahman, Myoung Jun Kim, et al. · Acute and Critical Care (2025) | TGRS Research Map | TGRS