What is the optimal sequential therapy after secondary IL-17A inhibitor failure in psoriasis: switching to an IL-23 inhibitor or to another IL-17A inhibitor?

An intraclass switch following IL-17A inhibitors failure yielded better treatment outcomes than a switch to guselkumab.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2025-12-11
DOI
https://doi.org/10.1080/09546634.2025.2588072
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

What is the optimal sequential therapy after secondary IL-17A inhibitor failure in psoriasis: switching to an IL-23 inhibitor or to another IL-17A inhibitor?

Yizhang Liu, Yehong Kuang, Kun Hu, Junchen Chen et al.
Journal of Dermatological Treatment
Psoriasis: Treatment and Pathogenesis
article

What is the optimal sequential therapy after secondary IL-17A inhibitor failure in psoriasis: switching to an IL-23 inhibitor or to another IL-17A inhibitor?

Yizhang Liu, Yehong Kuang, Kun Hu, Junchen Chen, Shuangyuan Zhou, Panpan Liu, Mi Zhang, Yongfang Duan
article en

Abstract

An intraclass switch following IL-17A inhibitors failure yielded better treatment outcomes than a switch to guselkumab.

Journal of Dermatological TreatmentVol. 36(1)
Central South University (CN), SKiN Health (CA), Parker Institute for Cancer Immunotherapy (US), Hunan Cancer Hospital (CN), National Clinical Research (US), Xiangya Hospital Central South University (CN)
Openalex Percentile: Top 54%
Psoriasis: Treatment and Pathogenesis
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What is the optimal sequential therapy after secondary IL-17A inhibitor failure in psoriasis: switching to an IL-23 inhibitor or to another IL-17A inhibitor? — Yizhang Liu, Yehong Kuang, et al. · Journal of Dermatological Treatment (2025) | TGRS Research Map | TGRS