Exploring the Systemic Immune-Inflammation Index as a novel biomarker for nonalcoholic fatty liver disease: a systematic review and meta-analysis
SII shows a significant association with NAFLD and may serve as a valuable, noninvasive biomarker for early detection and risk stratification. Despite promising results, the presence of heterogeneity and possible publication bias highlights the need for more standardized and longitudinal research to validate SII's clinical utility in NAFLD.
Authors
- Ehsan Amini‐Salehi (ORCID: https://orcid.org/0000-0003-4985-2899)
- Amir Nasrollahizadeh (ORCID: https://orcid.org/0000-0001-6328-8468)
- Hannaneh Nejati
- Herby Jeanty
- Saisree Reddy Adla Jala
- Abinash Mahapatro (ORCID: https://orcid.org/0009-0004-1645-5314)
- Seyyed Mohammad Hashemi (ORCID: https://orcid.org/0000-0003-3864-172X)
- Shika M Jain
- Mohit Mirchandani
- Satabdi Sahu
- Ghazalgoo Arezoo
Institutions
- Brooklyn Hospital Center (US)
- Montefiore Medical Center (US)
- Guilan University of Medical Sciences (IR)
- Maharaja Krishna Chandra Gajapati Medical College and Hospital (IN)
- MVJ Medical College and Research Hospital (IN)
- Hormozgan University of Medical Sciences (IR)
- Hi-Tech Medical College & Hospital (IN)
- Mission Hospital (US)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1097/ms9.0000000000004097
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00