PREVALENCE OF THE BRAF V600E MUTATION AMONG INDIGENOUS INDIVIDUALS WITH PAPILLARY THYROID CARCINOMA RESIDING IN A RADIATION-EXPOSED AREA.

The analysis revealed an association between the BRAF V600E mutation and papillary thyroid cancer in patients exposed to radiation from nuclear testing at the former SNTS. These findings offer new prospects for targeted therapy and early diagnosis of malignant thyroid neoplasms. Following the closure of the test site, positive developments in public health have been observed: radiophobia has decreased and the population's quality of life has improved. Furthermore, the adoption of iodine prophylaxis legislation and the country's industrial growth have contributed to improved well-being and better epidemiological outcomes for thyroid cancer in subsequent generations.