Prognostic Value of EZH2 and Ki-67 in Squamous Cell Carcinoma of Ear and Temporal Bone
Our study demonstrated that the overexpression of EZH2 was significantly associated with advanced tumor stage and poor 5-year overall survival in a Chinese ETBSCC cohort. These findings highlight the applicability of EZH2 as a candidate therapeutic target for integrated therapies. Further exploration and validation through a stable cell line are needed.
Authors
- Wei Li (ORCID: https://orcid.org/0000-0001-6286-200X)
- Xinyi Guo (ORCID: https://orcid.org/0000-0001-5416-7787)
- Zhi‐Qi Yin (ORCID: https://orcid.org/0000-0001-8989-6760)
- Yujie Zhang (ORCID: https://orcid.org/0000-0002-4686-6526)
- Mingfang Zhang (ORCID: https://orcid.org/0000-0001-8061-5694)
- Wenjuan Cai (ORCID: https://orcid.org/0000-0001-9200-5316)
- Zhandong Hu (ORCID: https://orcid.org/0000-0002-4647-0126)
Institutions
- Tianjin First Center Hospital (CN)
- Thales (Australia) (AU)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1097/mao.0000000000004668
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00